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KMID : 0370220210650020072
Yakhak Hoeji
2021 Volume.65 No. 2 p.72 ~ p.86
A Study on Safety and Drug Interactions of Herbal Drugs that Compose 100 Herbals Medication Prescriptions
Kim Jeong-Eun

Park Jong-Sun
Kim Do-Yeon
Yu Yae-Jin
Kim Ji-Eun
Lim Sung-Cil
Abstract
Currently in Korea, hundreds of herbs can be prescribed by an oriental medicine doctor or sold by a pharmacistto treat mild diseases or improve health conditions for the same indication. And it can be happened to the same patientat the same time. However, there is no monitoring system for the oriental medical doctors and pharmacists to check thedrug interaction or duplicate the administration. Herbal medicine contains pharmacologically bioactive ingredients, andwhen administered without assessment of the patient's disease and/or preexisting health conditions, it may overdose,duplicate, or showed unexpected harmful effects. The study was conducted through collecting information based on thesecondary research using PubChem, PubMed, etc. and the evaluation of various source of additional primary informationthrough literature survey. The result showed if 151 herbs use without caution under supervision or monitoring, those mayrevealed pregnancy contraindication, severe drug indications, liver, renal, cardiovascular, and/or gastrointestinal (GI)functions and blood glucose, etc. Only 61 herbs were identified to be safe for pregnant women and the most frequencyside effect is GI problems. In conclusion, the result is very meaningful but available information is still limited and needto further research in future.
KEYWORD
Herbal medication, safety, misuse, drug Interaction, pregnant woman
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